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| Gene | ERBB3 |
| Variant | positive |
| Impact List | unknown |
| Protein Effect | unknown |
| Gene Variant Descriptions | ERBB3 (HER3) positive indicates the presence of ERBB3 (HER3) mRNA and/or protein. |
| Associated Drug Resistance | |
| Category Variants Paths |
ERBB3 positive |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT02980341 | Phase Ib/II | Patritumab deruxtecan | Phase I/II Study of U3-1402 in Subjects With Human Epidermal Growth Factor Receptor 3 (HER3) Positive Metastatic Breast Cancer | Completed | USA | 1 |
| NCT06956690 | Phase Ib/II | ENV-501 | A Phase 1/2 Clinical Trial to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of HMBD-501 in Patients With HER3-Expressing Solid Tumors | Recruiting | USA | AUS | 0 |