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Gene ARID1B
Variant dec exp
Impact List none
Protein Effect no effect
Gene Variant Descriptions ARID1B dec exp indicates decreased expression of the Arid1b protein. However, the mechanism causing the decreased expression is unspecified.
Associated Drug Resistance
Category Variants Paths

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No Variant Reference Transcript is Available.
No transcript is Available.

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
ARID1B dec exp Advanced Solid Tumor predicted - sensitive Cisplatin Preclinical - Cell culture Emerging In a preclinical study, siRNA knockdown of ARID1B in cultured tumor cells resulted in increased sensitivity to Platinol (cisplatin), suggesting that tumors with ARID1B loss or inactivation may have increased response to DNA damaging agents (PMID: 24788099). 24788099