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Gene ROS1
Variant A887V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ROS1 A887V lies within the extracellular domain of the Ros1 protein (UniProt.org). A887V has been identified in the scientific literature (PMID: 29642553), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

ROS1 mutant ROS1 A887V

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Transcript NM_002944.3
gDNA chr6:g.117366228G>A
cDNA c.2660C>T
Protein p.A887V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011536049 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536056.2 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536057.4 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
NM_002944 chr6:g.117366228G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
NM_002944.3 chr6:g.117366228G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536055.2 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536049.3 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536055.3 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536058.3 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536058 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536055 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536057 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536054.2 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
NM_002944.2 chr6:g.117366228G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536054.3 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536057.3 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536056.3 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536049.2 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536056 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536054 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38
XM_011536058.2 chr6:g.117366258G>A c.2660C>T p.A887V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References