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Gene MSH6
Variant A1204E
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MSH6 A1204E lies within the ATPase domain of the Msh6 protein (PMID: 17531815). A1204E has been identified in sequencing studies (PMID: 22832583), but has not been biochemically characterized and therefore, its effect on Msh6 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

MSH6 mutant MSH6 A1204E

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Transcript NM_000179.3
gDNA chr2:g.47805672C>A
cDNA c.3611C>A
Protein p.A1204E
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406818.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
XM_024452819.1 chr2:g.47805672C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406825.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406824.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_000179.2 chr2:g.47805672C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406822.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406805.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406820.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406819.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406830.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406796.1 chr2:g.47805672C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406828.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
XM_011532799 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406821.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406797.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406800.1 chr2:g.47805672C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406804.1 chr2:g.47806246C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406827.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_000179 chr2:g.47805672C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406809.1 chr2:g.47805672C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_000179.3 chr2:g.47805672C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406808.1 chr2:g.47805672C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38
NM_001406801.1 chr2:g.47806558C>A c.3611C>A p.A1204E RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References