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Gene | TP53 |
Variant | N310I |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | TP53 N310I lies within the CCAR2, HIPK1, and CARM1-interacting region and bipartite nuclear localization signal region of the Tp53 protein (UniProt.org). N310I has not been characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Feb 2024). |
Associated Drug Resistance | |
Category Variants Paths |
TP53 mutant TP53 exon9 TP53 N310I |
Transcript | NM_000546.6 |
gDNA | chr17:g.7673599T>A |
cDNA | c.929A>T |
Protein | p.N310I |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001126112.3 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001407270.1 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001126112 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001407266.1 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_000546.5 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001126114.2 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001126112.2 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001407264.1 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001407262.1 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001126113.2 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001126114 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_000546.6 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001126113 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001407268.1 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_000546 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001126113.3 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
NM_001126114.3 | chr17:g.7673599T>A | c.929A>T | p.N310I | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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