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Gene TP53
Variant L308R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TP53 L308R lies within the HIPK1, CCAR2, and CARM1-interacting regions of the Tp53 protein (UniProt.org). L308R has not been characterized in the scientific literature and therefore, its effect on Tp53 protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon9 TP53 L308R

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Transcript NM_000546.6
gDNA chr17:g.7673605A>C
cDNA c.923T>G
Protein p.L308R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001126113 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_000546 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001126114 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001126112 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38
NM_001126113.3 chr17:g.7673605A>C c.923T>G p.L308R RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References