Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | TP53 |
Variant | K292Q |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | TP53 K292Q lies within the DNA-binding domain of the Tp53 protein (PMID: 20978130). K292Q has not been characterized in the scientific literature and therefore, its effect on Tp53 protein function is unknown (PubMed, Feb 2025). |
Associated Drug Resistance | |
Category Variants Paths |
TP53 mutant TP53 exon8 TP53 K292Q |
Transcript | NM_000546.6 |
gDNA | chr17:g.7673746T>G |
cDNA | c.874A>C |
Protein | p.K292Q |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |