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Gene | ROS1 |
Variant | L567V |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 L567V lies within fibronectin type-III domain 3 of the Ros1 protein (UniProt.org). L567V has been identified in sequencing studies (PMID: 27284491, PMID: 36422072), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Jan 2025). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 L567V |
Transcript | NM_002944.3 |
gDNA | chr6:g.117389410G>C |
cDNA | c.1699C>G |
Protein | p.L567V |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |