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Gene TET2
Variant L1514H
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TET2 L1514H lies within the catalytic domain of the Tet2 protein (PMID: 24315485). L1514H has not been characterized in the scientific literature and therefore, its effect on Tet2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

TET2 mutant TET2 L1514H

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Transcript NM_001127208.3
gDNA chr4:g.105275051T>A
cDNA c.4541T>A
Protein p.L1514H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_005263082.4 chr4:g.105275051T>A c.4541T>A p.L1514H RefSeq GRCh38/hg38
NM_001127208.2 chr4:g.105275051T>A c.4541T>A p.L1514H RefSeq GRCh38/hg38
XM_024454103.2 chr4:g.105275051T>A c.4541T>A p.L1514H RefSeq GRCh38/hg38
XM_024454102.2 chr4:g.105275051T>A c.4541T>A p.L1514H RefSeq GRCh38/hg38
XM_024454103.1 chr4:g.105275051T>A c.4541T>A p.L1514H RefSeq GRCh38/hg38
NM_001127208 chr4:g.105275051T>A c.4541T>A p.L1514H RefSeq GRCh38/hg38
XM_024454102.1 chr4:g.105275051T>A c.4541T>A p.L1514H RefSeq GRCh38/hg38
XM_005263082.3 chr4:g.105275051T>A c.4541T>A p.L1514H RefSeq GRCh38/hg38
XM_005263082 chr4:g.105275051T>A c.4541T>A p.L1514H RefSeq GRCh38/hg38
NM_001127208.3 chr4:g.105275051T>A c.4541T>A p.L1514H RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References