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| Gene | MDM2 |
| Variant | amp |
| Impact List | none |
| Protein Effect | no effect |
| Gene Variant Descriptions | MDM2 amp indicates an increased number of copies of the MDM2 gene. However, the mechanism causing the increase is unspecified. |
| Associated Drug Resistance | |
| Category Variants Paths |
MDM2 amp |
| Molecular Profile | Protein Effect | Treatment Approaches |
|---|---|---|
| MDM2 amp | no effect | MDM2 Inhibitor |
| MDM2 amp TP53 wild-type | ||
| ALK wild-type MDM2 amp TP53 wild-type | ||
| MDM2 amp TP53 loss | ||
| ALK amp MDM2 amp TP53 wild-type | ||
| BRAF G469A MDM2 amp | ||
| EML4 - ALK MDM2 amp | ||
| EML4 - ALK MDM2 amp TP53 wild-type | ||
| BRAF G469A MDM2 amp TP53 wild-type |