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Gene TP53
Variant A159G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TP53 A159G lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). A159G has been identified in sequencing studies (PMID: 37345120), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Dec 2023).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon5 TP53 A159G

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Transcript NM_000546.6
gDNA chr17:g.7675136G>C
cDNA c.476C>G
Protein p.A159G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001126114 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001126113 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001126113.3 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_000546 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001126112 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7675136G>C c.476C>G p.A159G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
TP53 A159G unknown