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Gene CSF3R
Variant L62Q
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CSF3R L62Q lies within the Ig-like C2-type domain of the Csf3r protein (UniProt.org). L62Q has not been characterized in the scientific literature and therefore, its effect on Csf3r protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

CSF3R mutant CSF3R L62Q

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Transcript NM_000760.4
gDNA chr1:g.36475553A>T
cDNA c.185T>A
Protein p.L62Q
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_172313 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
NM_156039 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
NM_172313.3 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_011540748 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
NM_156039.3 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_011540749 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_017000370 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
NM_172313.2 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_011540749.1 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
NM_156039.3 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_047446753.1 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_017000370.1 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_005270493 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
NM_000760 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
NM_000760.3 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_011540748.3 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_005270493.1 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_005270493.1 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
XM_011540749.1 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38
NM_000760.4 chr1:g.36475553A>T c.185T>A p.L62Q RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
CSF3R mutant bone marrow cancer not applicable N/A Clinical Study Emerging In clinical studies, high frequency of CSF3R mutations was identified in patients with chronic neutrophilic leukemia (PMID: 23656643, PMID: 24081659), suggesting that this may serve as a future diagnostic biomarker (PMID: 24441292). 24081659 23656643 24441292