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Gene | TP53 |
Variant | K305T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | TP53 K305T lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). K305T has not been characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Jan 2025). |
Associated Drug Resistance | |
Category Variants Paths |
TP53 mutant TP53 exon8 TP53 K305T |
Transcript | NM_000546.6 |
gDNA | chr17:g.7673706T>G |
cDNA | c.914A>C |
Protein | p.K305T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |