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TP53 K305T - Gene Variant Detail

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Gene TP53
Variant K305T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TP53 K305T lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). K305T has not been characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Jan 2025).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon8 TP53 K305T

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Transcript NM_000546.6
gDNA chr17:g.7673706T>G
cDNA c.914A>C
Protein p.K305T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001407268.1 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001126113.3 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001126114 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_000546 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001126112 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001126113 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7673706T>G c.914A>C p.K305T RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
TP53 K305T unknown