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Gene | TP53 |
Variant | A161P |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | TP53 A161P lies within the DNA-binding domain of the Tp53 protein (UniProt.org). A161P has been identified in the scientific literature (PMID: 27813088, PMID: 26723900), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Dec 2024). |
Associated Drug Resistance | |
Category Variants Paths |
TP53 mutant TP53 exon5 TP53 A161P |
Transcript | NM_000546.6 |
gDNA | chr17:g.7675131C>G |
cDNA | c.481G>C |
Protein | p.A161P |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |