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| Gene | TP53 |
| Variant | K164N |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | TP53 K164N lies within the DNA-binding domain of the Tp53 protein (PMID: 15510160). K164N has been identified in the scientific literature (PMID: 16546179, PMID: 30766968), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Aug 2025). |
| Associated Drug Resistance | |
| Category Variants Paths |
TP53 mutant TP53 exon5 TP53 K164N |
| Transcript | NM_000546.6 |
| gDNA | chr17:g.7675120C>G |
| cDNA | c.492G>C |
| Protein | p.K164N |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |