Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | TP53 |
Variant | Q167L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | TP53 Q167L lies within the DNA-binding domain of the Tp53 protein (PMID: 21760703). Q167L has been identified in the scientific literature (PMID: 11275993, PMID: 15050734, PMID: 32265839), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Feb 2024). |
Associated Drug Resistance | |
Category Variants Paths |
TP53 mutant TP53 exon5 TP53 Q167L |
Transcript | NM_000546.6 |
gDNA | chr17:g.7675112T>A |
cDNA | c.500A>T |
Protein | p.Q167L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_000546 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001126112.3 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001407268.1 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_000546.5 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001126114 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001407270.1 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001126112 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001126114.2 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001126113.3 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001407264.1 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001126112.2 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001407262.1 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_000546.6 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001126114.3 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001407266.1 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001126113 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
NM_001126113.2 | chr17:g.7675112T>A | c.500A>T | p.Q167L | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|