TP53 Q167L
Gene Variant Detail

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Gene TP53
Variant Q167L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TP53 Q167L lies within the DNA-binding domain of the Tp53 protein (PMID: 21760703). Q167L has been identified in the scientific literature (PMID: 11275993, PMID: 15050734, PMID: 32265839), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Aug 2025).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon5 TP53 Q167L

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Transcript NM_000546.6
gDNA chr17:g.7675112T>A
cDNA c.500A>T
Protein p.Q167L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001126113.3 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001126113 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001126114 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001126112 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_000546 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7675112T>A c.500A>T p.Q167L RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References