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Gene TP53
Variant C124G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TP53 C124G lies within the DNA-binding domain of the Tp53 protein (PMID: 21760703). C124G has been identified in sequencing studies (Journal of Thoracic Oncology, Vol 13, Issue 10, S987-S988), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Jan 2024).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon4 TP53 C124G

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Transcript NM_000546.6
gDNA chr17:g.7675999A>C
cDNA c.370T>G
Protein p.C124G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000546.6 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001126112 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_000546 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001126114 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001126113.3 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001126113 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7675999A>C c.370T>G p.C124G RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries