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Gene TP53
Variant I50S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TP53 I50S lies within the CCAR2 and HRMT1L2-interacting regions of the Tp53 protein (UniProt.org). I50S has not been characterized in the scientific literature and therefore, its effect on Tp53 protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon4 TP53 I50S

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Transcript NM_000546.6
gDNA chr17:g.7676220A>C
cDNA c.149T>G
Protein p.I50S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001407264.1 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001126113.3 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001126112 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001126114 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_000546 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38
NM_001126113 chr17:g.7676220A>C c.149T>G p.I50S RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries