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Gene | TP53 |
Variant | E358G |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | TP53 E358G lies within the HIPK1, CARM1 and HIPK2-interacting region of the Tp53 protein (UniProt.org). E358G has not been characterized in the scientific literature and therefore, its effect on Tp53 protein function is unknown (PubMed, Jan 2024). |
Associated Drug Resistance | |
Category Variants Paths |
TP53 mutant TP53 exon10 TP53 E358G |
Transcript | NM_000546.6 |
gDNA | chr17:g.7670636T>C |
cDNA | c.1073A>G |
Protein | p.E358G |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001126112.3 | chr17:g.7670636T>C | c.1073A>G | p.E358G | RefSeq | GRCh38/hg38 |
NM_001407262.1 | chr17:g.7670636T>C | c.1073A>G | p.E358G | RefSeq | GRCh38/hg38 |
NM_001126112 | chr17:g.7670636T>C | c.1073A>G | p.E358G | RefSeq | GRCh38/hg38 |
NM_001126112.2 | chr17:g.7670636T>C | c.1073A>G | p.E358G | RefSeq | GRCh38/hg38 |
NM_000546.6 | chr17:g.7670636T>C | c.1073A>G | p.E358G | RefSeq | GRCh38/hg38 |
NM_000546 | chr17:g.7670636T>C | c.1073A>G | p.E358G | RefSeq | GRCh38/hg38 |
NM_000546.5 | chr17:g.7670636T>C | c.1073A>G | p.E358G | RefSeq | GRCh38/hg38 |
NM_001407264.1 | chr17:g.7670636T>C | c.1073A>G | p.E358G | RefSeq | GRCh38/hg38 |
NM_001407266.1 | chr17:g.7670636T>C | c.1073A>G | p.E358G | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
TP53 E358G | unknown |