Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | PIK3CA |
Variant | D926N |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | PIK3CA D926N lies within the PI3K/PI4K domain of the Pik3ca protein (UniProt.org). D926N has been identified in sequencing studies (PMID: 30766968, PMID: 26099045), but has not been biochemically characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
PIK3CA mutant PIK3CA D926N |
Transcript | NM_006218.4 |
gDNA | chr3:g.179230113G>A |
cDNA | c.2776G>A |
Protein | p.D926N |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_006218 | chr3:g.179230113G>A | c.2776G>A | p.D926N | RefSeq | GRCh38/hg38 |
XM_011512894.2 | chr3:g.179230113G>A | c.2776G>A | p.D926N | RefSeq | GRCh38/hg38 |
NM_006218.4 | chr3:g.179230113G>A | c.2776G>A | p.D926N | RefSeq | GRCh38/hg38 |
XM_011512894 | chr3:g.179230113G>A | c.2776G>A | p.D926N | RefSeq | GRCh38/hg38 |
XM_006713658 | chr3:g.179230113G>A | c.2776G>A | p.D926N | RefSeq | GRCh38/hg38 |
XM_006713658.5 | chr3:g.179230113G>A | c.2776G>A | p.D926N | RefSeq | GRCh38/hg38 |
NM_006218.3 | chr3:g.179230113G>A | c.2776G>A | p.D926N | RefSeq | GRCh38/hg38 |
XM_006713658.4 | chr3:g.179230113G>A | c.2776G>A | p.D926N | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
PIK3CA D926N | unknown |