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Gene | PIK3CA |
Variant | Y165H |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | PIK3CA Y165H does not lie within any known functional domains of the Pik3ca protein (UniProt.org). PIK3CA Y165H has been identified in sequencing studies (PMID: 27548314), but has not been biochemically characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
PIK3CA mutant PIK3CA Y165H |
Transcript | NM_006218.4 |
gDNA | chr3:g.179199830T>C |
cDNA | c.493T>C |
Protein | p.Y165H |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_006713658.4 | chr3:g.179199830T>C | c.493T>C | p.Y165H | RefSeq | GRCh38/hg38 |
NM_006218.3 | chr3:g.179199830T>C | c.493T>C | p.Y165H | RefSeq | GRCh38/hg38 |
XM_011512894.2 | chr3:g.179199830T>C | c.493T>C | p.Y165H | RefSeq | GRCh38/hg38 |
XM_011512894 | chr3:g.179199830T>C | c.493T>C | p.Y165H | RefSeq | GRCh38/hg38 |
XM_006713658.5 | chr3:g.179199830T>C | c.493T>C | p.Y165H | RefSeq | GRCh38/hg38 |
NM_006218.4 | chr3:g.179199830T>C | c.493T>C | p.Y165H | RefSeq | GRCh38/hg38 |
XM_006713658 | chr3:g.179199830T>C | c.493T>C | p.Y165H | RefSeq | GRCh38/hg38 |
NM_006218 | chr3:g.179199830T>C | c.493T>C | p.Y165H | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
PIK3CA Y165H | unknown |