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Gene APC
Variant I1918V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC I1918V lies within the beta-catenin binding and downregulation region of the Apc protein (PMID: 14672538). I1918V has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC I1918V

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Transcript NM_000038.6
gDNA chr5:g.112841346A>G
cDNA c.5752A>G
Protein p.I1918V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001127510 chr5:g.112841346A>G c.5752A>G p.I1918V RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112841346A>G c.5752A>G p.I1918V RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112841346A>G c.5752A>G p.I1918V RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112841346A>G c.5752A>G p.I1918V RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112841346A>G c.5752A>G p.I1918V RefSeq GRCh38/hg38
NM_000038 chr5:g.112841346A>G c.5752A>G p.I1918V RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112841346A>G c.5752A>G p.I1918V RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112841346A>G c.5752A>G p.I1918V RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112841346A>G c.5752A>G p.I1918V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries