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Gene | NRAS |
Variant | act mut |
Impact List | unknown |
Protein Effect | unknown |
Gene Variant Descriptions | NRAS act mut indicates that the variant results in activation of NRAS downstream signaling. The mechanism causing the activation can include either loss of GTP hydrolysis activity (loss of function) or increased nucleotide exchange rate (gain of function). |
Associated Drug Resistance | |
Category Variants Paths |
NRAS mutant NRAS act mut |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
NRAS act mut | unknown | |
CDKN2A mut NRAS act mut | ||
FGFR3 rearrange NRAS act mut |