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Gene | HRAS |
Variant | act mut |
Impact List | unknown |
Protein Effect | unknown |
Gene Variant Descriptions | HRAS act mut indicates that the variant results in activation of HRAS downstream signaling. The mechanism causing the activation can include either loss of GTP hydrolysis activity (loss of function) or increased nucleotide exchange rate (gain of function). |
Associated Drug Resistance | |
Category Variants Paths |
HRAS mutant HRAS act mut |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
HRAS act mut | unknown |