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Gene TP53
Variant R273X
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TP53 R273X indicates a hotspot mutation resulting in an amino acid change at codon 273 of the Tp53 protein, which often results in a loss of Tp53 protein function.
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon8 TP53 R273X

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Transcript NM_000546.6
gDNA chr17:g.7673801_7673803
cDNA c.817_819
Protein p.R273
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001126113.3 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001126113 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_000546 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001126114 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001126112 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7673801_7673803 c.817_819 p.R273 RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries