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Gene CHEK1
Variant M1?
Impact List unknown
Protein Effect unknown
Gene Variant Descriptions CHEK1 M1? indicates a disruption of the methionine (M) start codon with an unknown translational effect on the Chek1 protein. M1? has not been characterized and therefore, its effect on Chek1 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

CHEK1 mutant CHEK1 M1?

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Transcript NM_001114121.2
gDNA chr11:g.125626769_125626771
cDNA c.1_3
Protein p.M1
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017017146 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001244846.1 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001114122.2 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_024448337.1 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_024448337.2 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_047426313.1 chr11:g.125626827_125626829 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001330427.1 chr11:g.125625761_125625763 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_047426312.1 chr11:g.125626573_125626575 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001114121.2 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_011542561 chr11:g.125625761_125625763 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001330428.1 chr11:g.125626827_125626829 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001274.5 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001330428.1 chr11:g.125626827_125626829 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_011542560 chr11:g.125625761_125625763 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001274 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001114122.3 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001114121.2 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_011542563 chr11:g.125626827_125626829 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_011542560.2 chr11:g.125625761_125625763 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001330427.2 chr11:g.125629246_125629248 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_011542562 chr11:g.125626573_125626575 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_011542560.3 chr11:g.125625761_125625763 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_017017146.2 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001114122 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001244846 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
XM_047426311.1 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001114121 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001244846.1 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38
NM_001274.5 chr11:g.125626769_125626771 c.1_3 p.M1 RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References