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Gene CHEK1
Variant G169S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CHEK1 G169S lies within the protein kinase domain of the Chek1 protein (UniProt.org). G169S has been identified in sequencing studies (PMID: 26168399, PMID: 22941188), but has not been biochemically characterized and therefore, its effect on Chek1 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

CHEK1 mutant CHEK1 G169S

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Transcript NM_001114121.2
gDNA chr11:g.125633243G>A
cDNA c.505G>A
Protein p.G169S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001244846.1 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001274.5 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001114121 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
XM_017017146.2 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001244846 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001274 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001244846.1 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001114121.2 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
XM_047426311.1 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001114122 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001114121.2 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001114122.2 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
XM_024448337.1 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
XM_017017146 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001114122.3 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
NM_001274.5 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38
XM_024448337.2 chr11:g.125633243G>A c.505G>A p.G169S RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries