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Gene CHEK1
Variant D336N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CHEK1 D336N does not lie within any known functional domains of the Chek1 protein (UniProt.org). D336N has not been characterized in the scientific literature and therefore, its effect on Chek1 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

CHEK1 mutant CHEK1 D336N

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Transcript NM_001114121.2
gDNA chr11:g.125644173G>A
cDNA c.1006G>A
Protein p.D336N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_024448337.1 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001114122.3 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001244846 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001274 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001114121.2 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
XM_017017146.2 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001274.5 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001274.5 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001114122 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001114121 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001244846.1 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001114121.2 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
XM_024448337.2 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
XM_047426311.1 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
XM_017017146 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001244846.1 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38
NM_001114122.2 chr11:g.125644173G>A c.1006G>A p.D336N RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References