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Gene TP53
Variant G105A
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TP53 G105A lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). G105A has not been characterized in the scientific literature and therefore, its effect on Tp53 protein function is unknown (PubMed, Jan 2024).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon4 TP53 G105A

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Transcript NM_000546.6
gDNA chr17:g.7676055C>G
cDNA c.314G>C
Protein p.G105A
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000546.5 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001126114 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001126113 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_000546 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001126113.3 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38
NM_001126112 chr17:g.7676055C>G c.314G>C p.G105A RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References