MSH6 I944V
Gene Variant Detail

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Gene MSH6
Variant I944V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MSH6 I944V lies within the clamp domain of the Msh6 protein (PMID: 17531815). I944V has not been characterized in the scientific literature and therefore, its effect on Msh6 protein function is unknown (PubMed, Apr 2025).
Associated Drug Resistance
Category Variants Paths

MSH6 mutant MSH6 I944V

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Transcript NM_000179.3
gDNA chr2:g.47800813A>G
cDNA c.2830A>G
Protein p.I944V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000179.2 chr2:g.47800813A>G c.2830A>G p.I944V RefSeq GRCh38/hg38
NM_001406798.1 chr2:g.47800813A>G c.2830A>G p.I944V RefSeq GRCh38/hg38
NM_000179 chr2:g.47800813A>G c.2830A>G p.I944V RefSeq GRCh38/hg38
XM_024452819.1 chr2:g.47800813A>G c.2830A>G p.I944V RefSeq GRCh38/hg38
NM_001406796.1 chr2:g.47800813A>G c.2830A>G p.I944V RefSeq GRCh38/hg38
NM_001406808.1 chr2:g.47800813A>G c.2830A>G p.I944V RefSeq GRCh38/hg38
NM_000179.3 chr2:g.47800813A>G c.2830A>G p.I944V RefSeq GRCh38/hg38
NM_001406809.1 chr2:g.47800813A>G c.2830A>G p.I944V RefSeq GRCh38/hg38
NM_001406800.1 chr2:g.47800813A>G c.2830A>G p.I944V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References