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MSH6 K185T - Gene Variant Detail

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Gene MSH6
Variant K185T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MSH6 K185T does not lie within any known functional domains of the Msh6 protein (UniProt.org). K185T has been identified in sequencing studies (PMID: 22810696), but has not been biochemically characterized and therefore, its effect on Msh6 protein function is unknown (PubMed, Apr 2025).
Associated Drug Resistance
Category Variants Paths

MSH6 mutant MSH6 K185T

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Transcript NM_000179.3
gDNA chr2:g.47795990A>C
cDNA c.554A>C
Protein p.K185T
Source Database RefSeq
Genome Build GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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