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Gene TP53
Variant E204G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TP53 E204G lies within the DNA-binding domain of the Tp53 protein (PMID: 22713868). E204G has been identified in the scientific literature (PMID: 8344494, PMID: 27149842), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Jan 2024).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon6 TP53 E204G

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Transcript NM_000546.6
gDNA chr17:g.7674920T>C
cDNA c.611A>G
Protein p.E204G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001126112.2 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126114 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126115.2 chr17:g.7670702T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126113.3 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126113 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_000546 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126115 chr17:g.7670702T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126112 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126115.1 chr17:g.7670702T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7674920T>C c.611A>G p.E204G RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References