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Gene | FLT3 |
Variant | N609K |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FLT3 N609K lies within the cytoplasmic domain of the Flt3 protein (UniProt.org). N609K has been identified in sequencing studies (PMID: 25847190), but has not been biochemically characterized and therefore, its effect on Flt3 protein function is unknown (PubMed, Apr 2024). |
Associated Drug Resistance | |
Category Variants Paths |
FLT3 mutant FLT3 exon14 FLT3 N609K |
Transcript | NM_004119.3 |
gDNA | chr13:g.28034092A>C |
cDNA | c.1827T>G |
Protein | p.N609K |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004119.2 | chr13:g.28034092A>C | c.1827T>G | p.N609K | RefSeq | GRCh38/hg38 |
NM_004119 | chr13:g.28034092A>C | c.1827T>G | p.N609K | RefSeq | GRCh38/hg38 |
NM_004119.3 | chr13:g.28034092A>C | c.1827T>G | p.N609K | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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