Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | FLT3 |
Variant | T628I |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FLT3 T628I lies within the protein kinase domain of the Flt3 protein (UniProt.org). T628I has been identified in sequencing studies (PMID: 25847190), but has not been biochemically characterized and therefore, its effect on Flt3 protein function is unknown (PubMed, May 2024). |
Associated Drug Resistance | |
Category Variants Paths |
FLT3 mutant FLT3 exon15 FLT3 T628I |
Transcript | NM_004119.3 |
gDNA | chr13:g.28033946G>A |
cDNA | c.1883C>T |
Protein | p.T628I |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004119 | chr13:g.28033946G>A | c.1883C>T | p.T628I | RefSeq | GRCh38/hg38 |
NM_004119.2 | chr13:g.28033946G>A | c.1883C>T | p.T628I | RefSeq | GRCh38/hg38 |
NM_004119.3 | chr13:g.28033946G>A | c.1883C>T | p.T628I | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|