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Gene | ROS1 |
Variant | K2228Q |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 K2228Q lies within the cytoplasmic domain of the Ros1 protein (UniProt.org). K2228Q has been identified in the scientific literature (PMID: 27882345, PMID: 25589003, PMID: 36422072), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 K2228Q |
Transcript | NM_002944.3 |
gDNA | chr6:g.117301025T>G |
cDNA | c.6682A>C |
Protein | p.K2228Q |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_002944.2 | chr6:g.117301025T>G | c.6682A>C | p.K2228Q | RefSeq | GRCh38/hg38 |
NM_002944 | chr6:g.117301025T>G | c.6682A>C | p.K2228Q | RefSeq | GRCh38/hg38 |
NM_002944.3 | chr6:g.117301025T>G | c.6682A>C | p.K2228Q | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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