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Gene | FGFR1 |
Variant | A263V |
Impact List | missense |
Protein Effect | no effect |
Gene Variant Descriptions | FGFR1 A263V lies within the Ig-like C2-type domain 3 of the Fgfr1 protein (UniProt.org). A263V demonstrates phosphorylation levels similar to wild-type Fgfr1 and is not transforming in culture (PMID: 26826182) and therefore, has no effect on Fgfr1 protein function. |
Associated Drug Resistance | |
Category Variants Paths |
FGFR1 mutant FGFR1 A263V |
Transcript | NM_023110.3 |
gDNA | chr8:g.38424657G>A |
cDNA | c.788C>T |
Protein | p.A263V |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |