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Gene MLH1
Variant A92T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MLH1 A92T lies within the ATPase domain of the Mlh1 protein (PMID: 22753075). A92T has not been characterized in the scientific literature and therefore, its effect on Mlh1 protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

MLH1 mutant MLH1 A92T

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Transcript NM_000249.4
gDNA chr3:g.37001021G>A
cDNA c.274G>A
Protein p.A92T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000249.3 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_001354628.2 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_001354630.1 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_001258271.2 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_001354628.1 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_001258271.1 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
XM_047448152.1 chr3:g.37004467G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_000249.4 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
XM_005265161 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_001354629.2 chr3:g.37004467G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_001258271 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_001354629.1 chr3:g.37004467G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_001354630.2 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
XM_005265161.3 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
NM_000249 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38
XM_005265161.2 chr3:g.37001021G>A c.274G>A p.A92T RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References