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Gene | HRAS |
Variant | V81M |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | HRAS V81M does not lie within any known functional domains of the Hras protein (UniProt.org). V81M has been identified in sequencing studies (PMID: 27612322, PMID: 24997986, PMID: 14616967), but has not been biochemically characterized and therefore, its effect on Hras protein function is unknown (PubMed, Jun 2024). |
Associated Drug Resistance | |
Category Variants Paths |
HRAS mutant HRAS V81M |
Transcript | NM_005343.4 |
gDNA | chr11:g.533815C>T |
cDNA | c.241G>A |
Protein | p.V81M |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001130442.3 | chr11:g.533815C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_001318054 | chr11:g.532728C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_176795.5 | chr11:g.533815C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_005343.3 | chr11:g.533815C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_001130442.2 | chr11:g.533815C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_001318054.2 | chr11:g.532728C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_001318054.1 | chr11:g.532728C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_005343 | chr11:g.533815C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_001130442 | chr11:g.533815C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_176795 | chr11:g.533815C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_176795.4 | chr11:g.533815C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
NM_005343.4 | chr11:g.533815C>T | c.241G>A | p.V81M | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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