Gene Variant Detail

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Gene HRAS
Variant A11S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions HRAS A11S does not lie within any known functional domains of the Hras protein (UniProt.org). A11S has been identified in the scientific literature (PMID: 22683711, PMID: 29210482), but has not been biochemically characterized and therefore, its effect on Hras protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS A11S

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Transcript NM_005343.4
gDNA chr11:g.534292C>A
cDNA c.31G>T
Protein p.A11S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_005343.4 chr11:g.534292C>A c.31G>T p.A11S RefSeq GRCh38/hg38
NM_176795.5 chr11:g.534292C>A c.31G>T p.A11S RefSeq GRCh38/hg38
NM_005343.3 chr11:g.534292C>A c.31G>T p.A11S RefSeq GRCh38/hg38
NM_176795.4 chr11:g.534292C>A c.31G>T p.A11S RefSeq GRCh38/hg38
NM_001130442.3 chr11:g.534292C>A c.31G>T p.A11S RefSeq GRCh38/hg38
NM_001130442.2 chr11:g.534292C>A c.31G>T p.A11S RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References