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Gene HRAS
Variant A66T
Impact List missense
Protein Effect unknown
Gene Variant Descriptions HRAS A66T does not lie within any known functional domains of the Hras protein (UniProt.org). A66T has been identified in sequencing studies (PMID: 22722201), but has not been biochemically characterized and therefore, its effect on Hras protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS A66T

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Transcript NM_005343.4
gDNA chr11:g.533860C>T
cDNA c.196G>A
Protein p.A66T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001130442.3 chr11:g.533860C>T c.196G>A p.A66T RefSeq GRCh38/hg38
NM_176795.5 chr11:g.533860C>T c.196G>A p.A66T RefSeq GRCh38/hg38
NM_005343.4 chr11:g.533860C>T c.196G>A p.A66T RefSeq GRCh38/hg38
NM_001130442.2 chr11:g.533860C>T c.196G>A p.A66T RefSeq GRCh38/hg38
NM_176795.4 chr11:g.533860C>T c.196G>A p.A66T RefSeq GRCh38/hg38
NM_005343 chr11:g.533860C>T c.196G>A p.A66T RefSeq GRCh38/hg38
NM_001130442 chr11:g.533860C>T c.196G>A p.A66T RefSeq GRCh38/hg38
NM_176795 chr11:g.533860C>T c.196G>A p.A66T RefSeq GRCh38/hg38
NM_005343.3 chr11:g.533860C>T c.196G>A p.A66T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
HRAS A66T unknown