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Gene | HRAS |
Variant | E162G |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | HRAS E162G does not lie within any known functional domains of the Hras protein (UniProt.org). E162G has not been characterized and therefore, its effect on Hras protein function is unknown (PubMed, Feb 2024). |
Associated Drug Resistance | |
Category Variants Paths |
HRAS mutant HRAS E162G |
Transcript | NM_005343.4 |
gDNA | chr11:g.532721T>C |
cDNA | c.485A>G |
Protein | p.E162G |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001130442.3 | chr11:g.532721T>C | c.485A>G | p.E162G | RefSeq | GRCh38/hg38 |
NM_005343 | chr11:g.532721T>C | c.485A>G | p.E162G | RefSeq | GRCh38/hg38 |
NM_001130442 | chr11:g.532721T>C | c.485A>G | p.E162G | RefSeq | GRCh38/hg38 |
NM_005343.4 | chr11:g.532721T>C | c.485A>G | p.E162G | RefSeq | GRCh38/hg38 |
NM_005343.3 | chr11:g.532721T>C | c.485A>G | p.E162G | RefSeq | GRCh38/hg38 |
NM_001130442.2 | chr11:g.532721T>C | c.485A>G | p.E162G | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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