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Gene MLH1
Variant D631H
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MLH1 D631H lies within the EXO1-interacting region and C-terminal dimerization domain of the Mlh1 protein (PMID: 22753075). D631H has not been characterized in the scientific literature and therefore, its effect on Mlh1 protein function is unknown (PubMed, Jul 2024).
Associated Drug Resistance
Category Variants Paths

MLH1 mutant MLH1 D631H

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Transcript NM_000249.4
gDNA chr3:g.37047678G>C
cDNA c.1891G>C
Protein p.D631H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001258271 chr3:g.37047678G>C c.1891G>C p.D631H RefSeq GRCh38/hg38
NM_001258271.1 chr3:g.37047678G>C c.1891G>C p.D631H RefSeq GRCh38/hg38
NM_001354628.2 chr3:g.37047678G>C c.1891G>C p.D631H RefSeq GRCh38/hg38
NM_001258271.2 chr3:g.37047678G>C c.1891G>C p.D631H RefSeq GRCh38/hg38
NM_001354628.1 chr3:g.37047678G>C c.1891G>C p.D631H RefSeq GRCh38/hg38
NM_000249.4 chr3:g.37047678G>C c.1891G>C p.D631H RefSeq GRCh38/hg38
NM_000249 chr3:g.37047678G>C c.1891G>C p.D631H RefSeq GRCh38/hg38
NM_000249.3 chr3:g.37047678G>C c.1891G>C p.D631H RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries