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Gene NRAS
Variant D154G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions NRAS D154G lies within the G domain of the Nras protein (PMID: 17384584). D154G has been identified in sequencing studies (PMID: 24816253, PMID: 22037554), but has not been biochemically characterized and therefore, its effect on Nras protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

NRAS mutant NRAS D154G

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Transcript NM_002524.5
gDNA chr1:g.114708644T>C
cDNA c.461A>G
Protein p.D154G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002524 chr1:g.114708644T>C c.461A>G p.D154G RefSeq GRCh38/hg38
NM_002524.4 chr1:g.114708644T>C c.461A>G p.D154G RefSeq GRCh38/hg38
NM_002524.5 chr1:g.114708644T>C c.461A>G p.D154G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References