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Gene NRAS
Variant I24L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions NRAS I24L lies within the G domain of the Nras protein (PMID: 17384584). I24L has been identified in sequencing studies (PMID: 22495314), but has not been biochemically characterized and therefore, its effect on Nras protein function is unknown (PubMed, Dec 2023).
Associated Drug Resistance
Category Variants Paths

NRAS mutant NRAS exon2 NRAS I24L

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Transcript NM_002524.5
gDNA chr1:g.114716091T>G
cDNA c.70A>C
Protein p.I24L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002524.5 chr1:g.114716091T>G c.70A>C p.I24L RefSeq GRCh38/hg38
NM_002524.4 chr1:g.114716091T>G c.70A>C p.I24L RefSeq GRCh38/hg38
NM_002524 chr1:g.114716091T>G c.70A>C p.I24L RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References