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Gene MLH1
Variant K241N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MLH1 K241N lies within the ATPase domain of the Mlh1 protein (PMID: 22753075). K241N has not been characterized in the scientific literature and therefore, its effect on Mlh1 protein function is unknown (PubMed, Nov 2023).
Associated Drug Resistance
Category Variants Paths

MLH1 mutant MLH1 K241N

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Transcript NM_000249.4
gDNA chr3:g.37014477A>C
cDNA c.723A>C
Protein p.K241N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001258271.2 chr3:g.37014477A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_001354629.2 chr3:g.37017537A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_000249.4 chr3:g.37014477A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_001354630.1 chr3:g.37014477A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_001258271.1 chr3:g.37014477A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_001354628.2 chr3:g.37014477A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_001354629.1 chr3:g.37017537A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_000249 chr3:g.37014477A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_000249.3 chr3:g.37014477A>C c.723A>C p.K241N RefSeq GRCh38/hg38
XM_047448152.1 chr3:g.37017537A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_001258271 chr3:g.37014477A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_001354628.1 chr3:g.37014477A>C c.723A>C p.K241N RefSeq GRCh38/hg38
NM_001354630.2 chr3:g.37014477A>C c.723A>C p.K241N RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
MLH1 K241N unknown