NRAS S106L - Gene Variant Detail

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Gene NRAS
Variant S106L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions NRAS S106L lies within the G domain of the Nras protein (PMID: 17384584). S106L has not been characterized in the scientific literature and therefore, its effect on Nras protein function is unknown (PubMed, Dec 2024).
Associated Drug Resistance
Category Variants Paths

NRAS mutant NRAS exon4 NRAS S106L

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Transcript NM_002524.5
gDNA chr1:g.114709702G>A
cDNA c.317C>T
Protein p.S106L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002524 chr1:g.114709702G>A c.317C>T p.S106L RefSeq GRCh38/hg38
NM_002524.4 chr1:g.114709702G>A c.317C>T p.S106L RefSeq GRCh38/hg38
NM_002524.5 chr1:g.114709702G>A c.317C>T p.S106L RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References