ERBB3 R103G
Gene Variant Detail

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Gene ERBB3
Variant R103G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ERBB3 (HER3) R103G lies within the extracellular domain of the Erbb3 (Her3) protein (UniProt.org). R103G has been identified in the scientific literature (PMID: 27044931), but has not been biochemically characterized and therefore, its effect on Erbb3 (Her3) protein function is unknown (PubMed, Jun 2026).
Associated Drug Resistance
Category Variants Paths

ERBB3 mutant ERBB3 R103G

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Transcript NM_001982.4
gDNA chr12:g.56085067C>G
cDNA c.307C>G
Protein p.R103G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001005915.1 chr12:g.56085067C>G c.307C>G p.R103G RefSeq GRCh38/hg38
NM_001982.4 chr12:g.56085067C>G c.307C>G p.R103G RefSeq GRCh38/hg38
NM_001982 chr12:g.56085067C>G c.307C>G p.R103G RefSeq GRCh38/hg38
NM_001005915.1 chr12:g.56085067C>G c.307C>G p.R103G RefSeq GRCh38/hg38
NM_001005915 chr12:g.56085067C>G c.307C>G p.R103G RefSeq GRCh38/hg38
NM_001982.3 chr12:g.56085067C>G c.307C>G p.R103G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References