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Gene FLT3
Variant K826fs
Impact List frameshift
Protein Effect unknown
Gene Variant Descriptions FLT3 K826fs results in a change in the amino acid sequence of the Flt3 protein beginning at aa 826 of 993, likely resulting in premature truncation of the functional protein (UniProt.org). K826fs has not been characterized in the scientific literature and therefore, its effect on Flt3 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

FLT3 mutant FLT3 exon20 FLT3 K826fs

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Transcript NM_004119.3
gDNA chr13:g.(28018532_28018533)
cDNA c.(2476_2475)
Protein p.K826fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004119.3 chr13:g.(28018532_28018533) c.(2476_2475) p.K826fs RefSeq GRCh38/hg38
NM_004119 chr13:g.(28018532_28018533) c.(2476_2475) p.K826fs RefSeq GRCh38/hg38
NM_004119.2 chr13:g.(28018532_28018533) c.(2476_2475) p.K826fs RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
FLT3 K826fs unknown