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Gene FLT3
Variant V825*
Impact List nonsense
Protein Effect unknown
Gene Variant Descriptions FLT3 V825* results in a premature truncation of the Flt3 protein at amino acid 825 of 993 within the protein kinase domain of the Flt3 protein (UniProt.org). V825* has not been characterized in the scientific literature and therefore, its effect on Flt3 protein function is unknown (PubMed, May 2024).
Associated Drug Resistance
Category Variants Paths

FLT3 mutant FLT3 exon20 FLT3 V825*

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Transcript NM_004119.3
gDNA chr13:g.28018534_28018535delGTinsTA
cDNA c.2473_2474delGTinsTA
Protein p.V825*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011535015.2 chr13:g.28018476_28018478delGTCinsTAA c.2473_2475delGTCinsTAA p.V825* RefSeq GRCh38/hg38
NM_004119.2 chr13:g.28018534_28018535delGTinsTA c.2473_2474delGTinsTA p.V825* RefSeq GRCh38/hg38
NM_004119 chr13:g.28018534_28018535delACinsTA c.2473_2474delGTinsTA p.V825* RefSeq GRCh38/hg38
XM_011535015.3 chr13:g.28018476_28018478delGTCinsTAA c.2473_2475delGTCinsTAA p.V825* RefSeq GRCh38/hg38
NM_004119.3 chr13:g.28018534_28018535delGTinsTA c.2473_2474delGTinsTA p.V825* RefSeq GRCh38/hg38
XM_011535015 chr13:g.28018476_28018478delGACinsTTA c.2473_2475delGTCinsTAA p.V825* RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References